Kalina Dimova

Laboratory Instructor in Biochemistry

Kalina Petrova Dimova

Contact & Office Hours

Ford Hall 215

413-585-3864

Education

Ph.D., International Max Planck Research School for Molecular Biology/University of Göttingen

B.A., Smith College

Biography

Kalina Dimova teaches the core biochemistry labs (BCH253 and BCH353), as well as advanced methods courses such as BCH390. In her capacities at the Center for Proteomics, Dimova supports faculty and student research in the experimental design and application of state-of-the-art mass spectrometry and biochemistry techniques to answer a variety of biological questions.


Representative Publications

Lipstein N, Schaks S, Dimova K, Kalkhof S, Ihling C, Kölbel K, Ashery U, Rhee J, Brose N, Sinz A, Jahn O. “Nonconserved Ca(2+)/calmodulin binding sites in Munc13s differentially control synaptic short-term plasticity.”Mol Cell Biol. 2012 Nov;32(22):4628-41

Dimova K, Metskas LA, Kulp M, Scordilis SP."Skeletal Muscle Gender Dimorphism From Proteomics". J. Vis. Exp. 2011 Dec 14;(58). doi:pii: 3536. 10.3791/3536.

Kawabe H, Neeb A, Dimova K, Young SM Jr, Takeda M, Katsurabayashi S, Mitkovski M, Malakhova OA, Zhang DE, Umikawa M, Kariya K, Goebbels S, Nave KA, Rosenmund C, Jahn O, Rhee J, Brose N. “Regulation of Rap2A by the ubiquitin ligase Nedd4-1 controls neurite development.” Neuron. 2010 Feb 11;65(3):358-72.

Rodríguez-Castañeda F., Maestre-Martínez M, Coudevylle N, Dimova K, Junge H, Lipstein N, Lee D, Becker S, Brose N, Jahn O, Carlomagno T, Griesinger C. “Modular architecture of Munc13/calmodulin complexes: dual regulation by Ca2+ and possible function in short-term synaptic plasticity.”EMBO J. 2010 Feb 3;29(3):680-91.

Dimova K, Kalkhof S, Pottratz I, Ihling C, Rodriguez-Castaneda F, Liepold T, Griesinger C, Brose N, Sinz A, Jahn O. “Structural insights into the calmodulin-Munc13 interaction obtained by cross-linking and mass spectrometry.”Biochemistry.2009 Jun 30;48(25):5908-21.

Dimova K, Kawabe H, Betz A, Brose N, Jahn O. “Characterization of the Munc13-calmodulin interaction by photoaffinity labeling.” Biochim Biophys Acta. 2006 Nov;1763(11):1256-65.